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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... #classification ... blood #disorders #leukemia ... #diagnosis #CML ... #CLL #AML #Map
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... Chronic leukemia ... -> AML: Blast crises ... thrombocytosis) CML ... cutaneous plaques) AML
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... (AML) • Chronic ... (CML) - Hemolytic ... Renal • Chronic ... endocrinology #causes
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... hemorrhage) • Chronic ... myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • EBV • CMV ... Age > 50 • Chronic ... #Causes #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic ... (CML) - associated ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic ... Eosinophilic Leukemia ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Marrow Failure • Chronic ... Myelogenous Leukemia ... (CML) • Felty ... progression to AML
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... Most cases are related ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... • Treatment algorithms