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Surviving Sepsis 1-Hour Bundle - Initial Resuscitation for Sepsis and Septic Shock 

#SurvivingSepsis #1Hour #OneHour #Bundle
Surviving Sepsis ... Resuscitation for Sepsis ... and Septic Shock ... Resuscitation #CriticalCare ... #Management
Operationalization of New Sepsis and Septic Shock Criteria #Diagnosis #Management #EM #IM #QSofa #Score #Sepsis #SepticShock
Operationalization of New Sepsis ... and Septic Shock ... Criteria #Diagnosis ... #Management #EM ... #QSofa #Score #Sepsis
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
and Management ... SHOCK is a subset ... shock are identified ... #Criteria #Diagnosis ... #SIRS #criticalcare
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
(1st line for septic ... is not desired (e.g ... (distributive, septic ... Some cases of septic ... #pharmacology #criticalcare
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... ) UOP > 0.5 cc/kg ... Differential #Diagnosis #criticalcare ... algorithm #treatment #management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Septic shock ... with Shock: Sepsis ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT ... #Septic #Shock
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
and Management ... telemetry, 12-Lead EKG ... - Septic ... #Diagnosis #Management ... #Summary #criticalcare
American College of Critical Care Medicine algorithm for time-sensitive, goal-directed stepwise management of hemodynamic support in
goal-directed stepwise management ... to next step if shock ... #CriticalCare # ... Peds #Pediatrics #Sepsis ... #Management #StepWise
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
>10% bands Sepsis ... Septic Shock • ... >2 mmol/L Management ... fluids (30 mL/kg ... #sirs #shock #lactate
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... Angiotensin - "Ang II" - Sepsis ... Vasopressors #Inotropes #management ... #criticalcare #