23 results
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... fasc Diagnostic Criteria ... day 2 + 3 BIDMC Infectious ... #STSS #treatment ... #management #diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome ... #treatment #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... cæxist with other infections ... Diagnostic Criteria ... KD #vasculitis #rheumatology ... #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... Histopathologic criteria ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Anemia (AIHA) Treatment ... Steroids - 1-2 mg/kg ... esp if severe disease ... Polyclonal: - Infection ... #management #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... : NSAIDS Treatment ... Prednisone 0.5-1mg/kg ... AOSD #diagnosis #rheumatology ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... of infections) ... • IVIg 2 g/kg/month ... #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Essential Criteria ... Exclusion of Mimics: Infectious ... 2019 ACR/EULAR Criteria ... IGG4 #Diagnosis #Management ... #Rheumatology