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diagnosis algorithm treatment pharmacology criticalcare gastroenterology cardiology checklist peds table differential medications pediatrics pulmonary covid19 primarycare guidelines syndrome clinical comparison
Amiodarone-Induced Lung Iniurv (AILI) - Timeline Hours to days (peri-procedurally): ARDS Days to months: DAH Weeks: Eosinophilic pneumonia Weeks to
Amiodarone-Induced Lung Iniurv (AILI ... Induced #LungIniurv #AILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... ) DILI Types: ... • Cholestatic DILI ... differential #Diagnosis #Management
HFNC compared to NIV HFNC: - Comfort - Higher comfort Eating, drinking and speaking less impaired -
preload - P-SILI ... /VILI - Lower risk ... #comparison #management
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Pharmacology #Causes #DILI
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 Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Injury (DILI ... Hepatitis Procedures Management ... gastroenterology #management
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
• Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Diagnosis Algorithm DILI ... injury, Previous DILI ... hepatitis #DILI
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
BrighamChiefs #DILI
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
• Iatrogenic: DILI
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili
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