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diagnosis differential hyperkalemia potassium gitelman high diuretics excretion hematology leukostasis medications pharmacology renal summary table tls tumor
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... • Tumor lysis ... syndrome • Metabolic ... Elimination: • AKI ... blockers - MCW Nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Summary Causes ... Hyperphosphatemia • Hypocalcemia ... Loop diuretics for ... #causes #treatment ... #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... • Triggers: Diuretics ... fever - ACS, AKI ... Syndrome: • Pathophysiology ... values: Elevated K,
Gitelman Syndrome - Management Treatment includes - Electrolyte replacement - K & Mg, preferably Cl salts
- Management Treatment ... In persistent hypokalemia ... , K sparing diuretics ... #Management #Treatment ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, K-sparing diuretics ... Acidosis, Cell Lysis ... , RTA Type IV, AI ... only if no clear cause ... #nephrology #K
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
sparing diuretics ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... differential #diagnosis #causes ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
sparing diuretics ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... differential #diagnosis #causes ... potassium #high #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... #diagnosis #nephrology ... #management #pathophysiology ... #Hypokalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Dermatomyositis) AKI ... - Pathophysiology ... Loop diuretics for ... Dialysis for severe hyperkalemia ... #Summary #causes
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
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