9 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Phosphatase and Bilirubin ... Laboratory #Metabolism #ASTALT ... #AlkPhos #Bilirubin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
LFTs) - Normal Values ... Alkaline phosphatase (AlkP ... LFTs #Laboratory #Values ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... week • Direct bilirubin ... normal AST/ALT AST ... #chemistry #diagnosis ... #differential #Hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... - Unconjugated Bilirubin ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... week • Direct bilirubin ... be abnormal AST ... #differential #diagnosis ... #algorithm #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... • Serum total bilirubin ... ) or metabolic liver ... Hepatitis #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... - Serum total bilirubin ... ) or metabolic liver ... #Hepatology #AIH
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... or sed rate): Value ... GCA, but normal values ... Start steroids if ... them, but urgent rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Activation #Syndrome #Diagnosis ... #Management #Hematology