52 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Proliferative Class V - Membranous ... Nephritis #SLE #Classification ... #Classes #differential ... #diagnosis #management ... #nephrology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... thalassemias • Membrane ... Intravascular Causes ... #classification ... #hematology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Deep coma (any cause ... injury, Early ALS ... differential #diagnosis #table ... #neurology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... by 12 months Classification ... • Class V - Membranous ... #rheumatology # ... nephrology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Thalassemia • RBC Membrane ... Non-lmmune #Anemia #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... Most cases diagnosed ... across the plasma membrane ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... (CVID, WAS), (neurologic ... not required in all ... patients if the cause ... #Workup #hematology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of ... gene encoding AVP-NPII ... uropathy, Metabolic causes ... Diabetes #Insipidus #Classification ... #Types #Nephrology
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
concept is that all ... anti–glomerular basement membrane ... #Diagnosis #Rheumatology ... Medium #Large #Classification
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table