16 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... • Hyperkalemia ... #TLS #Pathophysiology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Clinicians should also ... Renin-secreting tumor ... #hypokalemia ... algorithm #causes #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Renin-secreting tumor ... acid, Liddle's Syndrome ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Leukostasis: • Pathophysiology ... hyperviscosity syndrome ... • Pathophysiology ... hydration - Hyperkalemia
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Anticonvulsants as ... Stevens-Johnson Syndrome ... , asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... complications such as ... Renin secreting tumor ... differential #potassium #nephrology
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... The video highlights ... #clinical #video ... #ophthalmology ... #physicalexam #neurology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
the follow up video ... There was also high ... PhysicalExam #clinical #video ... #ophthalmology ... #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large also ... Reactive Arthritis, AS ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology