59 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... Hematology #Diagnosis #Workup
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
(DIC) Overview ... • Prolonged PT/PTT ... CNS involvement (2% ... PT/INR: ↑ • PTT ... INR < 2.3 - APTT
Coagulation Protein Tests (PT and PTT)

#Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... Tests (PT and PTT ... ) #Coagulation ... #Tests #PTT #algorithm
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
liver disease 2. ... prolong PT too 2. ... filling of tube 2. ... intravascular coagulation ... (DIC) c.
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... = Intrinsic = APTT ... Factors 1, 2, ... Factors 1, 2, ... @pinoygastro #Coagulation
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... (DIC) Platelet ... aggregation PT, aPTT ... consumption of coagulation ... small vessels #DIC
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
INR), Prolonged PTT ... INR), Prolonged PTT ... (INR), Normal PTT ... Differential #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... filling of tube) 2. ... intravascularcoagulation (DIC ... differential #hematology #coagulation
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Diagnosis and Workup ... Algorithm History ... LET, lipase, PT. aPTT ... Pain #Diagnosis #Algorithm ... #workup
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Differential Diagnosis Algorithm ... /uL Initial Workup ... iron studies, PT/aPTT ... Differential #Diagnosis #Algorithm ... #hematology #workup