12 results
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... serious bacterial infections ... “low risk” an infant ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... can mimic common infections ... : • Infection ... #management #treatment ... #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
and Management ... cæxist with other infections ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Infectious: Mycoplasma ... #management #treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... Renal Failure Treatment ... #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
proximal weakness, arms ... life-threatening Differential ... myasthenia Diagnosis ... precipitated by: Drugs, infection ... #management #neurology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Neutropenia - Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... Chediak-Higashi syndrome Infant ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... be present: • AIDS ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... Reversible course Differential ... Infection, Electrolyte ... epilepticus Treatment ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
extensors of the arms ... bouts of HTN Diagnostic ... Transverse Myelitis Treatment ... #management #neurology ... #differential