68 results
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEI Antihypertensive ... the following ACEIs ... Monitor BP, potassium ... #ACEInhibitor #ACEIs
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... , ARB, or ARNI AND ... before increasing ACEI ... Reducing: • ACEI ... or ARB • ARNI
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Stepwise Approach: ACE ... , ARB, ARNI → Beta-Blocker ... Inhibitor • Rapid low-dose ... -2 Inhibitor → ARNI
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
AngiotensinReceptorNeprilysinInhibitor #ACEi ... angiotensinreceptorblockers #ARB #ARNI
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE ... , ARB, ARNI
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does a lot ... with excreting potassium ... classes (Aliskiren, ACEI ... will increase potassium ... , which is why potassium
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... Pharmacology #Impaired #Potassium
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
intercalated cells - A Low ... ATPase - AEI ... Trimethoprim • Low ... Uropathy - ACEI
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Normal Acid-Base: Low ... Ureterosigmoidoscopy • HTN, Low ... Algorithm #causes #potassium ... #low #nephrology
Acute Mountain Sickness 
Low partial pressure of oxygen at high altitude 
• Stop ascent 
• Supportive
Mountain Sickness Low ... fluids, analgesia, ani