27 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
) and Treatment ... hypocalcemia Treatment ... hydroxide • Hyperkalemia ... - Standard treatment ... diagnosis #management #oncology
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... mmol/L - Consider cause ... and if treatment ... Prevention - Consider cause ... #management #algorithm
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... of Hyporeflexia and ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... differential #diagnosis #table
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... Thrombocytosis: cells lyse as ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
spontaneously (before any treatments ... malignancies Treatments ... 6L/day) • For hyperkalemia ... Lysis #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... leukapheresis - TLS ... hydration - Hyperkalemia ... Lysis #Syndrome #TLS
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... HIV, Influenza, TSS ... Treatment of underlying ... per day until stable ... Diagnosis #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Acidosis, Cell Lysis (TLS ... only if no clear cause ... Elimination (see Table ... Redistribution Treatments
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
Bradycardia Diagnostic and ... Management Algorithm ... LIFE THREATENING CAUSES ... & TREATMENT - ... Electrolytes (hyperkalemia