22 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Characteristics of Old and ... New Potassium-Binding ... #Binding #KBinders ... Kayexelate #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... increase dose as ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #pharmacology #table
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... Thrombocytosis: cells lyse as ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... acidosis (Types 1 and ... DrEricStrong #Hypokalemia ... Diagnosis #Low #Potassium ... #Table #Classification
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... Figure 3 is an algorithm ... , and Table 3 summarizes ... #Treatment
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pathophysiology ... works by directly binding ... - Hyperkalemia ( ... , in states of hypokalemia ... #Pharmacology #Pathophysiology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... Dialysis Serum potassium ... #potassium #high ... #treatment
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of ... Treatment of Metabolic ... 8.0 mg/dL • Potassium ... hydroxide • Hyperkalemia ... - Standard treatment
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
proportion to other findings ... ) BRASH Treatment ... • Aggressive treatment ... epinephrine (↑HR and ... diagnosis #management #pathophysiology
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Algorithm • Treat ... • Reconsider treatment ... parenteral potassium ... #Management #Algorithm ... #treatment #potassium