22 results
Endocarditis - Duke Criteria - Major and Minor

MAJOR CRITERIA: 
 - Persistently +ve blood culture for
Endocarditis - Duke ... Criteria - Major and ... - New valvular regurgitation ... Coxiella burnetii infection ... drug use - Fever
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
- Differential ... Acute Infective Endocarditis ... , Rheumatic Fever ... Aortic Aneurysms and ... #Differential #
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
mitral regurgitation ... Microbiology: Blood ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... • Blood cultures
Duke's Criteria for Infective Endocarditis
Definite IE - Pathologic Criteria:
 • Pathologic lesions - vegetation or intracardiac
for Infective Endocarditis ... OR • 1 major and ... - New valvular regurgitation ... Predisposition • Fever ... evidence of active infection
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... Subacute bacterial endocarditis ... arteritis • Bloody ... • Aortic regurgitation ... #joint #pain #differential
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... mitral regurgitation ... Microbiology: Blood ... Paradoxical emboli via ASD ... #Differential #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Red Flags: • Fever ... Schonlein Purpura - Endocarditis ... : • Complete blood ... for hepatitis B and
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... cultures, including blood ... tachycardia or fever ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... Symptoms: High fevers ... hemolytic #anemia #hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
inflammation or infection ... petechiae/purpura with fever ... gonococcal disease, endocarditis ... petechiae/purpura with fever ... #Diagnosis #Dermatology