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Non-infective endocarditis Characteristics and Pathophysiology

By Dr. Sara Dong @swinndong via #IDFellowCase

#ID  #Infectious Diseases  #Infections
#Differential
Non-infective endocarditis ... Characteristics and ... Pathophysiology ... Diseases #Infections ... #Differential #
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Primary and Secondary ... Rheumatic fever, Infective ... endocarditis, Myxomatous ... endocarditis, Ring ... #differential #diagnosis
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
- Differential ... Endocarditis, Acute ... - Leaflet: • Infection ... : Infective Endocarditis ... Aortic Aneurysms and
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... B, hepatitis C infection ... C infection • ... , infective endocarditis ... endocarditis
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Heart Failure • Infective ... Endocarditis ... • Mitral Regurgitation ... • Mitral Stenosis
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
Non-Infective Endocarditis ... embolize • Cannot differentiate ... absent How can we differentiate ... - Infectious Diseases ... Marantic #diagnosis #pathophysiology
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... Parenchyma: • Infection ... • Valvular (Mitral ... stenosis or regurgitation ... , Tricuspid endocarditis
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... and bacterial infections ... Pyogenic/focal infection ... endocarditis Non-Infectious ... Fever #Patterns #Differential
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... mitral regurgitation ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Marantic: Emboli > Regurgitation
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Regurgitation ( ... stenosis - Infective ... /marantic endocarditis ... #Mitral #Regurgitation ... Primary #Functional #Differential