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diagnosis cardiology infectiousdiseases fuo algorithm antibiotic arthritis bloodculture children chronic cnie comparison culture failure hepatology infections intermittent joint liver management
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #Causes #differential ... #culture #negative ... #Endocarditis #
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... but important causes ... #Infective #Endocarditis ... #diagnosis #differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Typhus, gram-negative ... Pyogenic/focal infection ... Non-Infectious Causes ... #Patterns #Differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Origin (FUO) - Differential ... • Infectious endocarditis ... Osteomyelitis • Occult abscess ... #FUO #Chronic #Differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Origin (FUO) - Differential ... Diagnosis • Infection ... tuberculosis, Abscess ... , Endocarditis,
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Differentiating NBTE from Infective ... Clinical features: Fever ... Clinical features: Fever ... in up to 30% of cases ... common, Aortic root abscess
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
• Coagulase-negative ... night sweats, fever ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Treat underlying cause
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Common bacterial causes ... • Enteric gram negative ... artery (e.g., endocarditis ... in those with concurrent ... children #peds #differential
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... aureus, Coagulase-negative ... night sweats, fever ... Persistent bacteremia/fevers ... #Differential #
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Failure - Differential ... Source control (abscess ... lines, osteo, endocarditis ... SJS, DIHS, drug fever
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