9 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
: Fever (50%), Depression ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain ... erythematosus #signs
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 9) Unexplained fever ... diagnosis #sle #clues ... #system #erythematosus ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Subacute bacterial endocarditis ... • Mitral regurgitation ... #differential # ... diagnosis #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... night sweats, fever ... Vascular: • Systemic ... Marantic (NTBE) Differential ... underlying cause + Systemic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint pain ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... • Bacterial endocarditis ... #Differential #
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... involves aortic and mitral ... night sweats, fever ... Vascular: • Systemic ... #Endocarditis #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... lupus erythematosus ... Vasculitis: • Fevers ... purpura: strong sign ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis: • Fevers ... purpura: Strong sign ... urticaria, recent viral ... #Diagnosis #Rheumatology