11 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Tubule Epithelial ... distal convoluted tubule ... receptor activity #Tubule ... #Nephrology #Diagnosis ... #Differential #Table
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
tubular acidosis ... tubular acidosis ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
gammopathy of renal ... syndrome • Proximal tubular ... #Differential #Diagnosis ... #Classification ... #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... diuretics after renal ... tubule diuretic ... tubule reabsorptive ... #Causes #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Differential Diagnosis ... - Diarrhea • RENAL ... unloading • Kidney ... filtration rate by tubulo-glomerular ... Pathophysiology #Nephrology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
- Differential Diagnosis ... tubular acidosis ... sedation, narcotics, CVA ... Interpretation #Diagnosis ... #Summary #Nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... tubular obstruction ... nephrotoxicity to kidney ... tubular cells ... causes #treatment #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... • Metabolic alkalosis ... disequilibrium syndrome • Diagnosis ... Excretion #Diuresis #Nephrology ... #Medications #Table
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... • Hypokalemia (renal ... tubular acidosis ... Gitelman #Syndrome #diagnosis ... #nephrology #management