35 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... Chloride • Urine Ca ... krithicism #Gitelman ... Bartter #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Urine Electrolyte Interpretation - AKI, Hyponatremia, Hypokalemia and Non-Gap Metabolic Acidosis

#Urine #Electrolytes #Interpretation #ULytes #AKI #FENa
Interpretation - AKI, Hyponatremia ... , Hypokalemia and ... #FENa #FEUrea #Nephrology ... #Diagnosis
BEHIND - Stroke Mimics Mnemonic
Brain: Mass, Hemorrhage, Contusion
Epilepsy: Post Ictal State, 
Hyponatremia, Hypogycemia
Intoxication, Infection
Neuro: Migraine, Multiple
Ictal State, Hyponatremia ... Mimics #Mnemonic #CVA ... #Neurology #Diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... #Differential #Diagnosis ... potassium #low #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... EABV) - Consider: Hypovolemia ... @NephroMD #hyponatremia ... #diagnosis #differential ... algorithm #causes #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... - Differential Diagnosis ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... - Differential Diagnosis ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... #Nephrology #Differential
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic Hyponatremia ... ON (UNa < 30): Hypovolemia ... #Algorithm #diagnosis ... #sodium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... distal convoluted tubule ... #Syndrome #diagnosis ... #nephrology #management