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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... - Differential Diagnosis ... PRE-Renal AKI: • Hypovolemia ... #Kidney #Injury ... #nephrology
Acute Kidney Injury - RIFLE and AKIN Criteria for Diagnosis and Classification of AKI
 • AKIN
Acute Kidney Injury ... and Classification ... #Kidney #Injury ... #Classification ... #nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Classification ... #Kidney #Injury ... #Classification ... #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Pre-Renal: • Hypovolemia ... #Kidney #Injury ... #nephrology #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... - Differential Diagnosis ... blood volume • Hypovolemia ... #Differential #Diagnosis ... #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... #Kidney #Injury ... #Differential #Diagnosis ... #Classification ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach to Acute ... Kidney Injury ( ... require urgent nephrology ... common culprits: Hypovolemia ... #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Renal failure (acute ... Hypokalemia ... Chronic progressive kidney ... #differential #diagnosis ... #causes #nephrology