19 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome from Bartter ... Chloride • Urine Ca ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... syndrome • Pseudo Bartter-Gitelman ... Rhabdomyolysis Treatment ... #Syndrome #diagnosis ... #nephrology #management
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... thiazide diuretics, Bartter ... syndrome, Gitelman ... potassium #low #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... acid transporter Bartter ... ascending limb Gitelman ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
↑ Aldosterone: Kidney ... Mg2+ deficiency, Bartter ... syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
- Differential Diagnosis ... Hypomagnesemia - Familial: Bartter ... syndrome and Gitelman ... with secondary, hypocalcemia ... #causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... • Diuretics, Bartter's ... syndrome, Gitelman's ... #differential #diagnosis ... algorithm #causes #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... #Algorithm #nephrology