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differential syndrome gitelman pathophysiology treatment algorithm alkalosis causes chloride defects diuresis diuretics encephalopathy epithelial excretion hyperkalemia hypokalemia inherited k medications
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects in Kidney ... Tubule Epithelial ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis ... #Differential #Table
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... → Hypokalemia Metabolic ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
resistance • Metabolic ... disequilibrium syndrome • Diagnosis ... irrigation • Management ... Excretion #Diuresis #Nephrology ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... #treatment #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... factor PRES Diagnosis ... narrowing on MRA/CTA ... Drug toxicity, Metabolic ... #management #neurology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... and Management ... Elimination (see Table ... Calcium 2-3g IV Ca-gluconate ... #potassium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Gitelman #Syndrome #diagnosis ... #nephrology #management
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