29 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... Bartter syndrome • Urine ... Chloride • Urine ... Bartter #Algorithm #nephrology ... #hypokalemia #diagnosis
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... Bartter syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Diagnosis Algorithm ... Polyuria = >3L ... nutrition), Azotemia LOW ... #Differential #Diagnosis ... #Algorithm #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
- Differential Diagnosis ... • Central Dl (Low ... Mimics (↑ urine ... - Strong Medicine ... #Causes #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... #Differential #Diagnosis ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
- Differential Diagnosis ... Urine Cl-: Vomiting ... (late) • High Urine ... Bartter Syndrome, Gitelman ... #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... alkalosis • Normal or low ... Hypocalciuria (spot urine ... #Syndrome #diagnosis ... #nephrology #management
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology ... #low
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... in the distal tubule ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology ... #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
- Differential Diagnosis ... Urine Cl-: Vomiting ... (late) • High Urine ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology