52 results
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease
1) Tubule and interstitium
2) Vasculature
3)
Kidney Syndromes ... Etiologies of Kidney Disease ... 1) Tubule and ... Renal #Kidney #Syndromes
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Onset Alzheimer's (1% ... - Presenilin 1 ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... prevalence of 1- ... in the distal tubule ... #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... #Pathophysiology ... #Diagnosis #Signs
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Kawasaki Disease ... febrile vasculitic syndrome ... years (peak at 1 ... #Kawasaki #Disease ... #Features #Signs
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Liver and Biliary Diseases ... 1) Hands: Clubbing ... rings in Wilson's disease ... Edema #biliary #physicalexam ... #signs #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... hemianopsia IGF-1 ... Carpal Tunnel Syndrome ... Cardiovascular disease ... Overproduction #diagnosis #signs
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... rubbing • Atopic diseases ... • Rizutti's Sign ... #Keratoconus #pathophysiology
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
conditions exist: (1) ... type 1 (reflex ... • SVC syndrome ... Lower #Extremity #PhysicalExam ... #Pathophysiology
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Hirschsprung disease ... #Downs #Syndrome ... #PhysicalExam # ... Features #Signs