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diagnosis management differential hematology signs symptoms erythematosus lupus monoclonal sle vasculitis activation algorithm arteritis autoimmune avs bee behcet cerebritis chronic
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... pain • Extra-CNS ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Differential Diagnosis Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... (CNS) dysfunction ... Liver function tests ... #Rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... central nervous system ... (CNS) involvement ... MRI lesions and clinical ... #neurology #noninflammatory
Headache Etiologies and Associated Spectrum of Severity of Disease by System Critical, Emergent and Non-Emergent Causes CNS, neurologic,
of Disease by System ... Critical, Emergent ... and Non-Emergent Causes ... CNS, neurologic ... vascular disease Ocular
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... • 8%-27% for CNS ... #Rheumatology #
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
include a: • Neurologic ... tympanic membrane • Neurologic ... auditory nerve (CN ... cause unknown) ... II ○ Susac’s syndrome
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