12 results
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Differential Diagnosis ... #causes #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... /psychiatric changes ... #Differential #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Hemoglobinuria (PCH ... intravascular hemolysis on ... hemolytic #anemia #hematology ... #diagnosis
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... An APD was noted ... the follow up video ... the hospital, diagnosed ... ophthalmology #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... lesions depends on ... involvement Cauda ... #differential #diagnosis ... #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Splenic Marginal Zone ... et diutinum Neurologic ... WAIHA • CAD • PCH ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... Lower roots -> Cauda ... decreased muscle tone ... MCTD, Sjogren syndrome ... #neurology #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... -48% depending on ... : >3 symptoms, or ... fluid overload, PCC ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... Transform to DLBCL, PML ... workup #oncology #hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... tested earlier than one ... after symptom onset ... nerve roots and cauda ... #neurology