13 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Continue ACEi or ... ADA/KDIGO Consensus ... evidence-based pharmacologic ... ADA #KDIGO #eGFR ... #Insulin #metformin
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
including most type 1 diabetics ... including most 2 diabetics ... Add sliding scale ... Weight #Based #pharmacology ... endocrinology #diabetes
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
for Type 1 Diabetes ... patients with type 1 diabetes ... They will also add ... SensitivityFactor #Type1 #Diabetes ... #DM1 #Pharmacology
SNRls (Serotonin/Norepinephrine Reuptake Inhibitors) - FDA Approved Indications 

Venlafaxine (Effexor) - GAD, MDD, Panic Disorder, SAD
Inhibitors) - FDA ... Cymbalta) - GAD, MDD, Diabetic ... #Indications #Pharmacology ... #Psychiatry #FDA
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... ketoacidosis (AKA ... • Diabetic ketoacidosis ... HHS) - partial insulin ... #differential #diagnosis
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Prevents excess DA ... and deficient DA ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... #differential #diagnosis
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... #differential #diagnosis
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Block action of DA ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Insulin dependent ... ASA class If ... ACEi/ARBs - Hold ... Diabetes regimen ... stratification #diagnosis