4912 results
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Liver Injury - Differential ... disproportionate increase in AST ... compared with AST ... Liver Injury Differential ... Liver #Injury #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
to liver than AST ... elevated ALP • AST ... NT: ↑ • ALP > AST ... hematoma) • AST ... chemistry #diagnosis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... or AST > ALP): ... • Severe - ALT ... • Moderate - ALT ... or AST): • US
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... to liver than AST ... elevated ALP • AST ... NT: ↑ - ALP > AST ... injury #hepatitis #differential
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... • R value = (ALT ... Transaminitis #diagnosis #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Bilirubin ↑ - AST ... #Hemolysis #Differential
Etiology of Acute Liver Failure – bolded entities are most likely to cause AST/ALT in the
likely to cause AST ... /ALT in the 1000s ... Transaminitis #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... CPK 5X ULN • AST ... /ALT Elevation 4 ... :1 ratio (AST declines ... Rhabdomyolysis #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Findings: • ↑AST ... /ALT (5-10x ULN) ... infiltration) Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Nucleotidase • ALT ... & AST normal or ... on but elevated as ... bile ducts Differential