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Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI ... Cast formation: ... oxidative iniury Treatment ... hour with goal urine ... hyperkalemia or ATN
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Weakness - Dark urine ... + myoglobin AKI ... Cast formation: ... hour with goal urine ... hyperkalemia or ATN
Urinary Casts in the setting of renal disease
#Clinical #Nephro #Urine #Microscopy #Casts #Comparison #Chart #ATN #AIN
Urinary Casts in ... the setting of renal ... Clinical #Nephro #Urine ... #Microscopy #Casts ... Comparison #Chart #ATN
Mixed Cellular Casts on Urine Microscopy

Degenerating mixed cellular cast - brightfield, unstained - from patient with
Mixed Cellular Casts ... on Urine Microscopy ... mixed cellular cast ... pneumococcal sepsis and AKI ... #clinical #Urine
Urine Microscopy and Casts - Image Atlas Key

- Squamous Epithelial Casts
- Transitional Epithelial Cells
- Renal Tubular
Urine Microscopy ... and Casts - Image ... Epithelial Cells - Renal ... Cast - Waxy Cast ... JoseTesser) #Urine
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
UOP/weights - Urine ... protein/Cr - Renal ... Liano 1996) - ATN ... CKD— 13% (mostly ATN ... and pre-renal)
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Light chain (LC) cast ... gammopathy of renal ... malignancies Treatment ... Cisplatin • ATN ... Kidney #Injury #AKI
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... cells - Normal • Renal ... also be seen if urine ... - Renal infection ... contamination #Urine
General approach to AKI - Checklist

Urine electrolytes & FENa - Previously, it was believed that urine
General approach to AKI ... - Checklist Urine ... differentiate between pre-renal ... and intrinsic renal ... @PulmCrit #AKI
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... Casts • Hyaline ... tubular necrosis (ATN ... #Urine #Microscopy