32 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... : - ANA > ... Management #Summary #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... • Pattern: The ANA ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... erythematosus #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... : - ANA > ... : - ANA > ... comparison #table #rheumatology ... #diagnosis #management
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Algorithm and Differential ... Diagnosis Baseline ... investigations depending on clinical ... , ANA, Anti-GBM, ... renal biopsy • Abdominal
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... Complex: Systemic lupus ... , anti-GBM ab, ANA ... , anti-CCP • CXR
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... function test, ANA ... #Diagnosis #Causes ... #Workup #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... mononeuritis multiplex WORKUP ... coagulopathy) • CBC w differential ... Goodpasture's cause ... Renal #Syndromes #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... - GI tract: abdominal ... such as systemic lupus ... LFT • ESR • ANA ... #diagnosis #rheumatology