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causes hematology management algorithm acidosis hodgkins lactate lymphoma oncology overview shock aniongap arteritis chronic comparison dehydrogenase disorders elevated erythematosus fatigue
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... Inflammation, Chronic Infection ... #MCV #Classification
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Extrinsic Causes: • Liver ... drug induced • Infections ... #classification
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Defects, Drugs, Liver ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... Diagnosis Algorithm ... brain injury • Infectious ... , Liver failure, ... #Causes #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Renal Failure • Liver ... Hematologic • Anemia ... • Malignancy Infectious ... Pulmonary Disease Neurologic
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Localized soft-tissue infection ... Clearance: Systemic liver ... #Diagnosis #criticalcare
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... changes), high MCV anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... RBCs, muscle, liver ... upon damage • Normal ... • Toxins • Infection
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... the spleen or liver ... translocation • Types: Classification ... also arise in normal ... #differential #
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... Diagnosis Framework ... Brucellosis • Liver ... Fever #Patterns #Differential ... #Diagnosis #intermittent
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