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algorithm hepatitis lfts transaminitis abscess aih autoimmune chemistry children dili drug gastroenterology idiosyncratic induced interpretation myelitis neurology patterns pediatrics peds
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential # ... Diagnosis #Management ... gastroenterology #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... #Injury #hepatology ... transaminitis #differential ... #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- If both are normal ... of ALP • Near normal ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... upper limit of normal ... #Management #Hepatology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... from contiguous focus ... ) • Traumatic injury ... children #peds #differential ... #diagnosis #hepatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Presentation: Injury ... bouts of HTN Diagnostic ... Sjogren's • CSF: - Abnormal ... #management #neurology ... #differential
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