11 results
management sle complications differential druginduced pathophysiology rheumatology treatment arteritis biliary chagas cholangitis cirrhosis comparison dil disease erythematosus gca giantcell heat
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... constitutional symptoms ... Discontinuation of causal ... #rheumatology #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... hair follicles -> causes ... keratinocytes but abnormal ... pathophysiology #diagnosis ... #signs #symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... involvement: Intractable nausea ... disorders (Systemic lupus ... #diagnosis #neurology ... #symptoms #signs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Jaundice (later manifestation ... #workup #hepatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
skin (16-32%): lupus ... anterior/posterior MSK ... heart (2-5%), liver ... (pain/abnormal ... #Management #Signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
- Differential Diagnosis ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... - Core temp normal ... #causes #stroke
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... #rheumatology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Manifestations depend ... systemic sx + signs ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Bilateral signs ... and/or symptoms ... Sjogren's • CSF: - Abnormal ... #management #neurology
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