17 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... Symptoms: Fatigue ... quadrant discomfort Signs ... Liver biopsy findings ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... /Liver failure ... PBC Signs and ... Symptoms: • 50 ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... function may be abnormal ... hepatitis: < 1 • Cirrhosis ... #algorithm #hepatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
primary biliary cirrhosis ... (PBC), or with ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... #Algorithm #Hepatology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Serum PO4 -> decr RBC ... Constipation - MSK ... #diagnosis #pathophysiology ... #symptoms #signs
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... 500 mg QD until normal ... #management #hematology