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diagnosis table endocrinology diabetic differential ketoacidosis management causes diabetes hhs nephrology pathophysiology testing algorithm cancer colon colorectal covid19 crc criticalcare
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Ketoacidosis (DKA ... Syndrome (HHS) Absolute ... → Glucosuria → Polyuria ... Polydipsia #dka ... pathophysiology #comparison
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
Ketosis Disorders - Comparison ... Ketoacidosis (DKA ... • Euglycemic DKA ... State (HHS) • DKA ... endocrinology #comparison
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA) DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... of an absolute ... In DKA, the normal ... hyponatremia, polyuria
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... pain • Nausea • Polyuria ... , and death DKA ... 200 mg/dL #DKA
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
symptoms of HHS/DKA ... : Both: Polyuria ... , hypotension) DKA ... #EM #IM #Endo #DKA
Polyuria - Differential Diagnosis Algorithm Urine Output > 3L /day Water Diuresis (Urine Osm <100 mOsm/kg) • Primary
Polyuria - Differential ... • Water and solute ... Renal Failure Solute ... • Exogenous solute ... load #Polyuria
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... pain • Nausea • Polyuria ... , and death DKA ... 200 mg/dL #DKA
Polyuria - Differential Diagnosis Algorithm Polyuria = >3L Urine output / 24 hours Urine osmolality = 2 (Na
Polyuria - Differential ... Diagnosis Algorithm Polyuria ... 300 mosm/kg • Solute ... Hyperglycemia, High solute ... Primary Polydipsia #Polyuria
Polyuria - Differential Diagnosis Solute Diuresis • Na intake/saline • Glucosuria: Hyperglycemia, SGLT-2 inhibitors • Urea: Exogenous
Polyuria - Differential ... Diagnosis Solute ... @kdjhaveri #Polyuria
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... look like overlap DKA ... #HHS #comparison ... endocrinology #comparison
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