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oncology mds myelodysplastic activation aplastic cerebritis common cvid differential erythematosus hypogammaglobulinemia immunodeficiency immunology leukemia lupus macrophage mas myelodysplasia platelets sapho
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Kawasaki, Nephrotic syndrome ... TPO, TPO-RA • Infections ... : Chronic infections ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infections: Pneumonia ... : • Nephrotic syndrome ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent infections ... Idiopathic • Infections ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Marrow Failure • Chronic ... isoniazid) • Antibiotics ... • Parvovirus infection ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... such as infectious ... #Rheumatology # ... diagnosis #management ... #Dermatology
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