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Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... Differential Diagnosis ... syndrome) Diagnosis ... #Diagnosis #Management
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... GH excess prior ... plate fusion -> acromegaly ... rare causes of acromegaly ... Overproduction #diagnosis
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs ... #Symptoms #Diagnosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly ... GrowthHormone #GH
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
- Differential Diagnosis ... Puberty Onset • GH ... Resistance • Acromegaly ... #Differential #Diagnosis
Hirsutism - Differential Diagnosis Defined as excessive dark, coarse, male-pattern hair growth Hirsutism causes in premenopausal women: •
- Differential Diagnosis ... Cushing's Syndrome, Acromegaly ... Cushing's Syndrome, Acromegaly ... #Differential #Diagnosis
Sellar / Pituitary Mass - Differential Diagnosis Algorithm Adenoma - Primary Anterior Pituitary - Secreting
- Differential Diagnosis ... Prolactin • GH ... #Differential #Diagnosis
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
Pituitary path • Acromegaly ... Classification #Diagnosis
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
- Differential Diagnosis ... Pseudo-hypoparathyroidism • Acromegaly ... #Differential #Diagnosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia. Neoplastic: • Intraorbital meningioma • Pituitary adenoma
Differential diagnoses ... Pituitary adenoma (GH ... #Differential #Diagnosis
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