881 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly ... Overproduction #diagnosis #signs
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... GrepMed Handbook Clinical ... : • Classic Acromegaly ... resistance pseudo-acromegaly ... thakre_anuj) #Acromegaly
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly
Thyroid Eye Signs 
Lid Signs
    Dalrymple’s Sign: Lid Retraction.
    Von
Thyroid Eye Signs ... Lid Signs ... Dalrymple’s Sign ... Von Graefe’s Sign ... OPHTHALMOLOGY #clinical
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Acromegaly ... #Acromegalic #Hand
Corrigan's Sign in Severe Aortic Regurgitation

- Dr. Andres S. Kohan https://twitter.com/KohanAndres

#Corrigans #AorticRegurgitation #Pulse #PhysicalExam #Video #Neck
Corrigan's Sign ... #Video #Neck #Signs ... #Cardiology #Clinical
Brudzinski's Sign in Meningitis

Forced flexion of the neck elicits a reflex flexion of the hips. It
Brudzinski's Sign ... #Brudzinskis #Signs ... #PhysicalExam #Clinical
Muller's sign in Aortic Regurgitation - Systolic pulsations of the uvula 

In chronic severe aortic regurgitation,
Muller's sign in ... variety of physical signs ... Müller's sign is ... #Mullers #sign # ... regurgitation #uvula #clinical