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Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... resistance pseudo-acromegaly ... Diagnosis and Workup ... thakre_anuj) #Acromegaly
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... GH excess prior ... GH excess after ... plate fusion -> acromegaly ... rare causes of acromegaly
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly ... GrowthHormone #GH
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... Hypoparathyroidism, Acromegaly ... Diagnosis #Framework #Workup
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly
#ACROMEGALY #management #algorithm #treatment
#ACROMEGALY #management
Causes of Approach to Altered Level of Consciousness - Workup
Clinical Exam - Focal
 • Trauma
 •
Consciousness - Workup ... Refer to Blood Work ... Altered #ALOC #Workup ... #diagnosis #workup
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... Clinical #Photo #Acromegaly ... #Acromegalic #Hand
Thrombocytopenia - Workup Algorithm
A common consult I receive.

Dr. Joseph Shatzel @Clotmaster

#Thrombocytopenia #Workup #Algorithm #Diagnosis #Differential #Hematology
Thrombocytopenia - Workup ... Thrombocytopenia #Workup