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Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... metabolic abn #GrowthHormone
#ACROMEGALY #management #algorithm #treatment
#ACROMEGALY #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... and Management ... Differential Diagnosis ... MRI+contrast Management ... #Diagnosis #Management
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
Acromegaly Caused ... #Acromegaly #Signs ... #Symptoms #Diagnosis
Hirsutism - Differential Diagnosis Defined as excessive dark, coarse, male-pattern hair growth Hirsutism causes in premenopausal women: •
- Differential Diagnosis ... Cushing's Syndrome, Acromegaly ... Cushing's Syndrome, Acromegaly ... #Differential #Diagnosis
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
Pituitary path • Acromegaly ... Classification #Diagnosis
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
- Differential Diagnosis ... Pseudo-hypoparathyroidism • Acromegaly ... #Differential #Diagnosis
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Endocrinopathies - Acromegaly ... Myopathy #mimics #diagnosis
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
- Differential Diagnosis ... Hypoparathyroidism, Acromegaly ... #Differential #Diagnosis
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