3489 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... harmful -> Th Cells activate ... Allergy #Immunology #pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
responses gets activated ... antibodies which can cause ... Rheumatic #Fever #Pathophysiology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
coagulation has been activated ... age, which can cause ... Ddimer #dimer #pathophysiology
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
consists of an activated ... Initiation phase caused ... models #hematology #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
20 follicles re-activated ... , progesterone causes ... #OvarianCycle #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... Americans (18-71 cases ... survival is 93-95% Pathophysiology ... dysregulation: activated ... symptoms are not caused
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
plasminogen is activated ... tissue plasminogen activator ... Fibrinolysis #Pathway #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
• Liver -> GHR activates ... • Bone - IGFIR activates ... Muscle -> GHR activates ... Tissue -> GHR activates ... endocrinology #pathophysiology
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
IL-4 activates B ... when they are activated ... immunopathogenesis #Pathophysiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
TF-FVIIa also activates ... Once activated the ... models #hematology #pathophysiology