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diagnosis rheumatology management lupus pathophysiology sle erythematosus immunology disease hematology systemic treatment algorithm allergy classification criteria differential druginduced gammopathy monoclonal
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... predominance, Relapsing-remitting ... course +++ Clinical ... Breillat #Clarksons
Remitting Seronegative Symmetrical Synovitis Pitting tenosynovitis. Pink hands also. Hint: pink hands may not be related to
Remitting Seronegative ... Janetbirdope #Remitting ... Pitting #Edema #clinical
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 C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... is rare Normal complement ... response: The complement ... cell membranes -> Critical
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... dead tissue • Complement ... activation of complement
Admitting in the ICU - Checklist VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ... NOTES: The last clinic ... the Pt's current clinical ... depending on the clinical ... @EmmGeezee #Admitting
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... activation • Complement ... tagged with C3 complement ... - Activate Complement ... : Abs activate complement
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... leak syndrome (Clarkson's ... Monoclonal #Gammopathy #Clinical
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... abdominal pain and vomitting ... ARUPLabs #C1INH #Complement
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Early and Late Clinical ... joints - Remitting
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Erythematosus Clinical ... Immunologic Criteria CLINICAL ... anticoagulant - Low complement
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