11 results
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... and Chronic Kidney ... 3A, 3B, or 4 Diabetes ... #CKD3 #CKD4 #Dosing ... #Pharmacology #
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Contraindications: • Chronic kidney ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
initiation of treatment ... ml/min per 1.73 m2 ... with metformin. ... evidence-based pharmacologic ... #Diabetes #CKD #
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
3 months Pre-Renal ... Atheroemboli • Renal ... hypoperfusion Post-Renal ... Proteinuria) • Diabetes ... Hyperphosphatemia #CKD
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
medication for treatment ... of type 2 diabetes ... attention to patients renal ... #Pharmacology # ... Mechanism #Diabetes
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
elderly, chronic kidney ... (stage IV or V CKD ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... patients have renal ... double check the kidney ... DPP4 #Inhibitors #Renal ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... insulin dose for renal ... #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Inhibitors of Renal ... Tolvaptan) • Treatment ... #Diuretics #Renal ... Diuresis #Nephrology #Pharmacology