7 results
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... and Chronic Kidney ... 3A, 3B, or 4 Diabetes ... #CKD3 #CKD4 #Dosing ... #Pharmacology #
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Contraindications: • Chronic ... kidney disease: ... Summary #DM2 #diabetes ... #endocrinology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
3 months Pre-Renal ... Atheroemboli • Renal ... hypoperfusion Post-Renal ... Proteinuria) • Diabetes ... Hyperphosphatemia #CKD
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
patients. elderly, chronic ... kidney disease ... (stage IV or V CKD ... #endocrinology ... #diabetes #DM2
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Inhibitors of Renal ... Tolvaptan) • Treatment ... #Diuretics #Renal ... Diuresis #Nephrology #Pharmacology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... patients have renal ... double check the kidney ... DPP4 #Inhibitors #Renal ... #DM2 #Endocrinology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
Patients with Chronic ... Kidney Disease ... diagnosis: • Renal ... , uncontrolled diabetes ... #Pruritus #Treatment