11 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... their Disease Associations ... #Associations # ... diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
and Management ... patient with known AAA ... de novo between aorta ... compression of AAA ... or within the aorta
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Retroperitoneum and aorta ... conventional imaging (aorta ... serum lgE, no autoantibodies ... #management #phenotypes ... workup #treatment #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Asia • HLA-B51 association ... ) Differential Diagnosis ... Glucocorticoids 5-ASA ... #management #signs ... #symptoms #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Workup: - ANA ... months) and of autoantibodies ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... (also seen in association ... Mechanic's hands Autoantibodies ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Myoglobin Association ... Dermatomyositis: • ILD was diagnosed ... Dermatomyositis #diagnosis ... #management #rheumatology