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management differential lupus sle erythematosus ana antibodies druginduced vasculitis antibody antineutrophil arteritis autoimmune biliary bronchiectasis cholangitis cirrhosis classification comparison cryofibrinogenemia
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... Jcortesizaguirr #ANA ... #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (ANA) ANA or Anti-NucIear ... context of other symptoms ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management Summary ... - CRP: Usually normal ... Workup: - ANA ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... (ANA) - 95% - Initial ... Erythematosus #SLE #Summary ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... < 30 years - Aorta ... Symptoms (Sx) in ... LFT • ESR • ANA ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Discontinuation of causal ... months to years) Systemic ... Workup: - ANA ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... < 30 years • Aorta ... fluid (CSF) is abnormal ... tract, and often causes ... #Rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) - Summary ... intralobular bile ducts causes ... PBC Signs and Symptoms ... patients • +ANA ... Differential Diagnosis
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Bronchiectasis - Summary ... inflammation Symptoms ... - BAR >1.0 is abnormal ... Laboratory: • ANA ... , RF, CCP, ANCA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
laboratory findings (ANA ... : • ANCA-associated ... Induced Lupus: • Symptoms ... Serositis Labs: • ANA ... antibodies • (-) ANA
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