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lupus sle druginduced erythematosus systemic arthritis carcinoma comparison criticalcare differential dil disease hemophagocytic hlh igg4 lymphohistiocytosis phenotypes prs pulmonary rcc
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... life-threatening • Treatment ... of SLE • Evolution ... #Management #Summary ... #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
orientation, Biopsy ... orientation): ... #management #phenotypes ... #workup #treatment ... #rheumatology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... viral arthritis Workup ... count, and crystal evaluation ... MH/CCF/CWRU EM ... #Management #Summary
Shock - Diagnosis and Management Summary • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... and Management ... Inotropes - Adrenal ... #Management #Summary ... #criticalcare #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary ... severe disease & renal ... severe disease Treatment ... #diagnosis #rheumatology ... #management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
(RCC) - Diagnosis ... and Management ... disease Imaging and Treatment ... with contrast Evaluation ... #Management #Summary
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Unknown cause Treatment ... inhibitors under evaluation ... #management #treatment ... #summary #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... mononeuritis multiplex WORKUP ... & DIAGNOSIS Labs ... #differential #diagnosis ... #management #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... cutaneous-DIL • Evolution ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
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