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diagnosis management differential algorithm criticalcare causes clinical cardiology classification pocus table treatment allergy pathophysiology comparison ultrasound types pharmacology cardiogenic checklist
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... conjunctivitis • Anaphylaxis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... exposure to a likely allergen ... exposure to known allergen ... Angioedema #Anaphylaxis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Local and systemic anaphylaxis ... hay fever, food allergies ... , and drug allergies
Shock - Differential Diagnosis Algorithm Warm Extremities - Distributive Shock - Low JVP
Shock - Differential ... - Distributive Shock ... Sepsis • Anaphylaxis ... - Cardiogenic Shock ... - Obstructive Shock
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Bedside Classification of Shock Hypovolemic shock - Vomiting, diarrhea, overdiuresis - Hemorrhage (GI, peritoneal, RP) Distributive shock
Classification of Shock ... Hypovolemic shock ... Distributive shock ... - Septic shock ... Adrenal crisis - Anaphylaxis
Shock - Differential Diagnosis by Classification Hypovolemic (Intravascular volume depletion) - Hemorrhagic • Trauma
Shock - Differential ... - Septic - Anaphylaxis ... a.k.a. neurogenic shock ... DrEricStrong #Shock
Shock Types and Classification DISTRIBUTIVE 66% • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic • Warm
Shock Types and ... • Sepsis/SIRS, anaphylaxis ... Cold and Dry #Shock
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