9 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... #SLE #Mucocutaneous ... Manifestations #pathophysiology ... #diagnosis #signs
On the left we see a chest film with a typical finger-in-glove shadow.
The HRCT shows focal
On the left we see ... the appropriate clinical ... #Clinical #Radiology ... #CXR #CTChest # ... FingerInGlove #Sign
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... Purpura, Urticaria Chest ... erythematosus #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... Sjogrens #Syndrome #Pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
hair follicles -> Alopecia ... Pericarditis) -> Chest ... pleural effusion on CXR ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus (SLE ... titer, ACE level, CXR ... years with neck, chest ... ANA and RF (if clinical
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... e.g. incidental CXR ... skin (16-32%): lupus ... Diagnosis #Management #Signs
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
Pathogenesis and Clinical ... therapy - Lupus ... steroid use) - Radiation ... AvascularNecrosis #pathophysiology ... #diagnosis #signs
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
pain as non-radiating ... Vital signs: BP ... This patient’s clinical ... x-ray (CXR), try ... not seen on a CXR