31 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #Medications #Differential ... #LiverInjury #Hepatology ... #DILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... (>1000): • DILI ... #Differential # ... Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... tox) Search for alternative ... causes • Hepatocellular ... #hepatology
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential ... #algorithm
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Liver Mass - Differential Diagnosis Algorithm
Benign Cystic 
 • Cyst
 • Polycystic Liver Disease
 • Caroli's
Liver Mass - Differential ... Diagnosis Algorithm ... #Mass #Hepatology ... #Differential # ... #Causes
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... Trauma: Shock liver ... • Iatrogenic: DILI ... #Diagnosis #causes ... #hepatology
Liver Mass - Differential Diagnosis Algorithm
Cystic:
 • Benign 
     - Simple: Simple
Liver Mass - Differential ... Diagnosis Algorithm ... #Mass #Differential ... #Diagnosis #Algorithm ... #Causes #Hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Diagnosis Algorithm ... effect following treatment ... #Causes #Hematology